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Particle Replication in Non-wetting Templates: PRINT®print_feature 
Developed in the DeSimone Lab, PRINT is a top-down  nanofabrication process that allows for precise control over particle size, shape, and composition. PRINT enables the development of particles for novel applications in both Life
and Materials Science.     Read More...

UNC Dept. of Chemistry:  DeSimone Group Research Highlights
 
 

Latest News



http://naturesearch.org/
Tuesday, 8 May 2012 15:39


Recent accolades!
 
jing-xuJing Xu has successfully defended her dissertation! Jing and Kelly (Chang) McGowan are the most recent DeSimone group students to achieve their PhDs.

twssayonarasuckerTammy Shen has placed 3rd in the annual CHANL Scientific Art Competition for her piece entitled "Sayonara Sucker," depicting particles entering cells (pictured here).

Yapei Wang, yapei-wangformer DeSimone group postdoc, has joined Renmin University as a full professor.

  Congratulations, all!



http://naturesearch.org/
Tuesday, 1 May 2012 20:27


DeSimone elected to NAS
jmdss3Congratulations to Professor DeSimone, who was elected into the National Academy of Sciences today!  “I am excited and humbled by this tremendous honor,” said DeSimone. “This would not have been possible without the hard work of my students and staff who continue to propel our innovative research forward.” DeSimone and NSF Director, Subra Suresh (pictured), were meeting when they both received calls that they'd been elected to NAS.
UNC news release  nc state release

Monday, 30 Apr. 2012 22:41


detter_apr2012Prestigious honors for Detter!
Matthew Detter has been named a recipient of The Venable Medal, presented annually to the two most outstanding senior chemistry majors. Matthew was also recently chosen from a pool of over 3,500 to participate in the National Conference on Undergraduate Reserach in Ogden, Utah. Congratulations, Matthew!  read more...

Thursday, 19 Apr. 2012 15:38


NC Museum of Natural Sciences - Free events Saturday
nrcgrandopening
Prof. DeSimone will give two talks this Saturday, April 21st, during the 24-hour grand opening of the Nature Research Center at the NC Museum of Natural Sciences in Raleigh. The first talk, scheduled for 9:00 am, takes place in the Museum's exciting new Daily Planet multimedia venue (pictured). At 10:45 am he will give a presentation in the 2nd floor Windows on Research area.
  read more...

Click here for maps & event schedules


http://naturesearch.org/
Monday, 16 Apr. 2012 11:07


Napier selected for prestigious honor
massey_napier_apr2012Congratulations to Prof. Mary Napier, who was recently selected to receive UNC's 2012 C. Knox Massey Distinguished Service Award, which recognizes "unusual, meritorious or superior contributions" by University employees. Napier will be honored at a April 28th awards luncheon.  read MORE

Tuesday, 3 Apr. 2012 14:22


TODAY! - Innovations in Public Health lecture
desimone_smallAt 5:30 pm today Prof. DeSimone will deliver the 2012 Innovations in Public Health lecture, "Micro Particles, Macro Impact," at UNC's Gillings School of Global Public Health.
register & Learn more...

Friday, 9 Mar. 2012 19:14


DeSimone featured on Discovery.com Curiosity Project
cphomepagejmd3912Today, Discovery's Curiosity Project is featuring Prof. DeSimone as its "Resident Expert"! The Curiosity Project provides an innovative forum for experts from many fields to discuss important issues and answer some of the biggest questions of our time.

Check out Prof. DeSimone's Curiosity page herE
!

Wednesday, 7 Mar. 2012 09:23


Carolina and entrepreneurship
theatlanticThe Atlantic recently called attention to UNC's leadership in innovation and entrepreneurship, noting Chancellor Thorp's view of Dr. DeSimone's work as a "best-case scenario" for an entrepreneurial university. read FULL ARTICLE

Friday, 17 Feb. 2012 15:23


Pure drug PRINT particles
candenewslogoA recent C&E News article calls attention to the ability to manufacture pure drug nanoparticles using the PRINT technology. read C&EN ARTICLE

Tuesday, 31 Jan. 2012 21:59


NCI Features PRINT, Nano Letters paper
warefta-hasanA January National Cancer Institute news release has featured PRINT's promise for the treatment of prostate cancer. The release highlights findings recently published in Nano Letters by a DeSimone group team led by Dr. Warefta Hasan. read NCI's NEWS RELEASE
Read Nano Letters paper

Tuesday, 31 Jan. 2012 23:55


PRINT: A win for team science!
uncnsfstcCheck out NSF's 2012 "Profiles of Team Science" article on the legacy of the UNC Center for Environmentally Responsible Solvents and Processes (CERSP). Demonstrating the power of team science, CERSP's work led serendipitously to the PRINT technology. "It just shows the unbounded opportunities that happen when you get a bunch of good people together from different disciplines that are open-minded," says Prof. DeSimone.
read the full article!
access "Profiles in Team Science" in full

Wednesday, 11 Jan. 2012 20:25

Parrott appointed Assistant Professor at UNC-SOM
parrot_matthewCongrats to DeSimone group postdoc, Dr. Matthew Parrott, on his new appointment as an Assistant Professor in UNC's Department of Radiology in the School of Medicine! With his extensive background in nanotechnology, nuclear chemistry, and molecular imaging, Dr. Parrott will focus on rapidly screening polymers as potential imaging agents and optimizing the delivery of nanoparticles to improve drug efficacy. In addition to his new role, Dr. Parrott will continue to collaborate with the DeSimone group and the Carolina Institute for Nanomedicine to assist with the development of nanoparticle-platforms on campus. Read More...

Tuesday, 13 Dec. 2011 21:05


DeSimone TEDMED talk now online!
jmdtedmedtalk
Click Here to watch!

Thursday, 8 Dec. 2011 19:34

DeSimone wins Sigma Xi innovation award
chubbinnovationsigmaxiProf. DeSimone has been named the winner of the 2012 Walston Chubb Award for Innovation. This honor is awarded by Sigma Xi to recognize research into new areas of potential scientific importance, novel approaches to a long-standing problem in science or engineering, or research that may create a new methodology of importance to science or engineering.

Thursday, 1 Dec. 2011 16:39

Detter continues to rake in honors
detterphibetakappaCongratulations to Matthew Detter, who has been inducted into the Alpha of North Carolina Chapter of Phi Beta Kappa! Detter is one of only three students from the Department of Chemistry to be inducted this cycle. For Detter, the recognition comes on the heels of receiving several other awards for outstanding achievement. Read more about Detter's achievements HeRE and HeRE!

Tuesday, 15 Nov. 2011 20:11


Detter wins Sigma Xi poster competition, Texas Medical Center awarddettersigmaxiaward
Matthew Detter took first place in the undergrad poster competition (chemistry category) held last weekend at the Sigma Xi Annual Meeting & International Research Conference in Raleigh. “I truly enjoyed presenting my work to a professional audience, and I was thrilled to have my research recognized at such a prestigious conference,” said Detter. Yesterday, Detter was also selected for a travel award to attend the Higher Education Symposium on Translational Research and MD/PhD Career Development Workshop at the Texas Medical Center. read more...

Tuesday, 15 Nov. 2011 10:15


Liquidia releases video, YouTube channel
liqyoutubeIn 2004 Prof. DeSimone founded Liquidia Technologies based on the PRINT technology invented at UNC. Last week Liquidia launched a YouTube channel, featuring a new video. “It's exciting to see our work in the lab being translated to real world applications,” said Tammy Shen, current DeSimone group grad student pursuing a PhD in Molecular Pharmaceutics. “The video features some of the benefits that a collaboration with Liquidia offers, and provides a unique opportunity to envision where our own projects will go,” added Cathy Fromen, who is working toward a PhD in Chemical Engineering. Both Shen and Fromen are responsible for images in the video. watch video

Wednesday, 9 Nov. 2011 18:42


DeSimone elected to Research Triangle rtplogoFoundation board
Prof. DeSimone has been elected to the Research Triangle Foundaiton's Board of Directors. Says DeSimone, "The Triangle is a powerful economic engine for our region. I'm honored to have this opportunity to play a role in the strategy for our future economic growth."   READ More...

Wednesday, 9 Nov. 2011 16:39


NSF white papersnsf
Prof. DeSimone co-authored two recent NSF white papers, one on basic research and the other on broadening the participation of underrepresented groups in STEM fields.
read "New Directions for Broadening Participation in MPS"
read "At the Foundation of the Foundation: Basic Research at the NSF"

Wednesday, 19 Oct. 2011 15:08 (updated 31 Oct.)

DeSimone speaks at TEDMED
tedmed2011joedesimone2011
On October 28th Prof. DeSimone delivered a talk at the annual TEDMED conference in San Diego.
medgadget

Thursday, 27 Oct. 2011 12:28

ncialliance_print_technology_annualbulletin_picture2011_2NCI highlights PRINT
The National Cancer Institute Alliance for Nanotechnology in Cancer has featured PRINT in its annual bulletin. read HERE

Wednesday, 26 Oct. 2011 08:59

radioinvivoTeamwork in Science
For a special edition of Radio In Vivo, Carrboro's WCOM-FM 103.5 featured Prof. DeSimone's August keynote address delivered at the Burroughs Wellcome Fund's Science Education Annual Conference. click to Listen

Wednesday, 19 Oct. 2011 12:59

Detter discusses undergraduate research
matthew_detter_oct2010The News & Observer has published Matthew Detter's letter to the editor highlighting the value of independent research as part of the undergrad experience at UNC. read it here!

Tuesday, 18 Oct. 2011 10:12

Wall Street Journal Tech Innovation Award
wsj_techinnovaward_abbottstentThe Wall Street Journal has named Abbott’s ABSORBTM bioresorbable vascular scaffold a 2011 Technology Innovation Award winner. In 2002, Prof. DeSimone played a central role in developing this device, which provides the same support for clogged vessels as metal stents but fully dissolves once...read More...
ABBOTT's presS Release
wall street journal article

Tuesday, 11 Oct. 2011 08:24

matthew_detter_oct2010Detter wins undergrad research excellence award
Congratulations to Matthew Detter, the 2011 recipient of the James Maguire Memorial Award, recognizing outstanding undergraduate research and academic excellence. A member of the DeSimone group since June 2010, Detter's research has focused on the co-encapsulation of a steroidal hormone and a superparamagnetic targeting agent within high aspect ratio PRINT nanoparticles. The properties of these particles demonstrate promise for the localized and sustained treatment of arthritis, asthma, and other inflammatory conditions. read More...

Friday, 7 Oct. 2011 13:26
2011 Mendal Medal awarded to DeSimone
Villanova University has named mendalmedalProf. DeSimone the 2011 Mendel Medalist. The Mendel Medal was established in 1928 in honor of Gregor Mendel.
read More...

Wednesday, 14 Sept. 2011 14:21
DeSimone on 21st centurty invention
earthskyandfastcompanyEarthSky has posted the full podcast of its recent interview with Dr. DeSimone. Fast Company magazine has also highlighted the interview. earthsky
fast company

Friday, 26 August 2011 15:07
DeSimone featured on EarthSky program
earthsky1_8.26"What is our future?", the latest EarthSky 22 podcast, features an interview with Prof. DeSimone. Click here for the podcast, and listen for Prof. DeSimone shortly after minute 16!

Monday, 15 August 2011 17:30
$1 million for prostate cancer vaccine work
pcflogoA new Challenge Award from the Prostate Cancer Foundation will enable Prof. DeSimone and other lab members to collaborate with researchers from Beth Israel Deaconess Medical Center/Harvard, Johns Hopkins, and Liquidia on developing a nanoparticle vaccine for prostate cancer. read More...
UNC Health Care news Release
WCHL / chapelboro.com Feature

Wednesday, 22 July 2011 10:37
unc_liq_gates_imageUnique partnership
The July issue of Nature Biotech. highlights the Gates Foundation's recent $10 million investment in Liquidia Technologies. The investment sets a unique precedent for partnerships among philanthropies, other investors, and biotech companies with shared interestes in addressing global health issues...Read More...
SeE Also: FierceVaccines article

Wednesday, 13 July 2011 18:44
Microlens array article 'most read' soft_matter_cover_july_2011
Read "Biomimetic microlens array with antireflective "moth-eye" surface", featured on the cover of the July 21st issue of Soft Matter. The article was also among the top ten most-read articles in May for the online version of Soft Matter. Read More...

Thursday, 23 June 2011 17:02
FDA consults with Liquidia on nanomaterials
gen_imgGenetic Engineering & Biotechnology News highlights Liquidia's input on a recently released FDA draft guidance on nanotechnology. Read ARTICLE

Wednesday, 8 June 2011 16:18
Future Faculty Workshop: Diverse Leaders of Tomorrow - June 19-21
Prof. DeSimone will participate in the 4th annual Future Faculty Workshop: Diverse Leaders of Tomorrow, hosted by MIT. The workshop will provide mentorship to underrepresented minority students aspiring to become independent academic researchers..Read More...

Tuesday, 7 June 2011 11:29
NCSSM commencement address
ncssmgrad2011Prof. DeSimone delivered the keynote address at the N.C. School of Science and Mathematics 2011 Commencement ceremony. Read More...

Monday, 6 June 2011 15:32
DeSimone a finalist for E&Y Entrepreneur of the Year  
Prof. DeSimone and Neal Fowler, CEO of Liquidia Technologies, have been selected as finalists for the 2011 Ernst & Young Entrepreneur of the Year® award for the Carolinas. Read More...

Friday, 3 June 2011 08:12
Popular Mechanics features Merkel's research
pop_mechA recent edition of Popular Mechanics examines five promising techniques for the production of synthetic blood. Among these is Tim Merkel's red blood cell mimic research, highlighted as a promising method for mass production. Read article

Tuesday, 17 May 2011 14:51
Merkel delivers commencement address
tim_merkel_2011Congratulations to Tim Merkel, who was selected to deliver the Student Commencement Address at this year's Chemistry Commencement Ceremony based on his oustanding achievements as a graduate student. Tim's speech provided encouragement to fellow graduates, emphasizing preserverance in the face of obstacles and following passions even when doing so leads to difficult choices. download commencement program

Monday, 16 May 2011 08:39
PRINT featured in PharmTech
pharmtech_may2011In a recent issue of Pharmaceutical Technology, Erik Greb highlights PRINT's promise as an emerging technology for manufacturing inhalable drug particles.  Read More...

Thursday, 28 April 2011 13:15
Napier appointed Research Associate Professor
mary-napierCongratulations to Dr. Mary Napier on her new appointment in UNC's Department of Biochemistry and Biophysics as Research Associate Professor! In addition to her new role, Prof. Napier will continue in her current capacity in the DeSimone Group.

Friday, 8 April 2011 10:37  (updated 28 Apr.)
Notable achievements!tim_merkel_2011
Congrats to Tim Merkel for successfully defending his dissertation on April 6th! Tim has also been named a finalist for the 2011 DSM Polymer Technology Award, which recognizes excellence in innovative PhD research in polymer technology. The theme for the 2011 award is Polymers at the Biology-Materials Science Interface. The winner will be selected at the Fall National ACS Meeting in Denver.

Tuesday, 29 March 2011 12:59  (updated 31 Mar.)
Wang receives $3M start-up; will join BCM faculty
jin_wang_sept2010Congratulations to DeSimone Group postdoc, Dr. Jin Wang, who will join the Baylor College of Medicine (BCM) faculty this coming fall as a Cancer Prevention Research Institute of Texas (CPRIT) Scholar in Cancer Research. Wang is the recipient of a $2 million CPRIT award for new faculty, which recognizes investigators with the ability to make outstanding contributions to the field of cancer research, promote inquiry into new areas, foster collaboration, and stimulate growth in the field. A $1 million match from Baylor brings the total to $3 million. Wang will serve as assistant professor in the Department of Pharmacology at BCM, member of the NCI-designated Dan L. Duncan Cancer Center, and adjunct faculty in the Department of Bioengineering at Rice University. Read More...

Thursday, 24 March 2011 09:59
DeSimone named WCHL Hometown Hero
wchlimageYesterday, WCHL named Prof. DeSimone a Hometown Hero for his exemplary service and dedication to others in the community. Read More...
Listen to Interview

Friday, 4 March 2011 14:42
Gates Foundation invests $10 million in Liquidia     
The Bill & Melinda Gates Foundation's new $10 million investment in Liquidia Technologies will support the development of vaccines and therapeutics. Liquidia was founded by Prof. DeSimone and colleagues in 2004 based on the PRINT technology.
C&E News Feature
daily Tar HeeL Feature
XCONOMY Seattle feature
UNC research spotlight
News & Observer Feature
Liquidia/Gates News Release

Wednesday, 23 February 2011 15:36
DeSimone discusses PRINT on radio program
arewealone_feb2011"Nano Nano," an episode of the science radio program Are We Alone, will be broadcast this week on podcast sites and public radio stations nationwide. Check out Prof. DeSimone's segment here!
full episode  about "Are We Alone"

Thursday, 17 February 2011 15:23  (updated 21 Feb.)
DeSimone receives 2010 AAAS Mentor Award
desimone_smallProf. DeSimone was presented with the 2010 AAAS Mentor Award during a February 19th ceremony at the 2011 AAAS Annual Meeting in Washington, DC. The award honors DeSimone's dedication to advancing diversity in the chemistry PhD workforce. AAAS News Release

Thursday, 10 February 2011 13:15
Merkel discusses synthetic red blood cell research at national forum
merkel_innovation_summit_feb2011Yesterday, The Atlantic hosted a live digital town hall discussion titled “Finding Work, Finding Our Way: Building the Economy & Jobs of the Future.” DeSimone group grad student Tim Merkel discussed his recent research and the potential for synthetic blood. UNC-CH Chancellor Holden Thorp also discussed UNC's focus on entrepreneurship and innovation. Read More... Watch Video

Thursday, 10 February 2011 13:00
DeSimone named PMSE fellow
The ACS Division of Polymeric Materials: Science & Engineering (PMSE) has named Prof. DeSimone as one of its 2011 fellows. Read More

Tuesday, 8 February 2011 09:53
Collaboration explores use of PRINT to enhance efficacy of malaria vaccines
Liquidia Technologies, founded by Prof. DeSimone in 2004, has announced a collaboration with the PATH Malaria Vaccine Initiative (MVI) to explore the use of PRINT® technology to design next generation malaria vaccines. MedCity News Feature

Tuesday, 25 January 2011 16:53
cathy-fromenFromen takes 2nd place for poster
Congratulations to Cathy Fromen, who placed 2nd in yesterday's poster competition at NC State's Schoenborn Presentations event! read MorE..

Friday, 21 January 2011 10:33
James ByrneByrne awarded Schwirck Fellowship
Congratulations to James Byrne, this year's recipient of the Scott Neil Schwirck Fellowship for Medical Research!
read MorE..

Thursday, 10 January 2011 17:09  (updated 4 Mar.)
tim_merkel_2011
Tim Merkel
PNAS paper draws widespread attention
A study released in the January 10th Early Edition of PNAS calls attention to advancements in the development of red blood cell mimics. Led by DeSimone group grad student, Tim Merkel, the study has earned attention from Nature News, C&E News, the News & Observer...read MORE...
NATURE NEWS fEature
NATURE Biotech Research Highlight
Nt'l Academy of Engineering/ WTOP Radio SEGMENT
Reesenews Video Graphic Feature
News & Observer Story
C&E News Concentrate
UNC NEWS RELEASE
Download PNAS Paper

Thursday, 6 January 2011 17:23
Tech transfer paper makes top 10 list again
Facilitating the Commercialization of University Innovation: The Carolina Express License Agreement”, by Professor DeSimone and Lesa Mitchell of the Kauffman Foundation, explores new practices developed at UNC-Chapel Hill to improve processes involved in commercializing university research. Learn More

Tuesday, 20 December 2010 15:08
Nanotech in N.C.     Last week's Local Tech Wire piece, "Nanotech: Big future in N.C. for science of small particles," paints a picture of opportunity for nanotechnology in North Carolina. Read ARTICLE

Tuesday, 7 December 2010 13:02  (updated 14 Dec.)
Matt Parrott
Matt Parrott
Chris Luft
Chris Luft
JACS paper highlighted in C&E News
Novel biomaterial developed in the DeSimone group has been highlighted in the “News of the Week” section of Chemical and Engineering News, in addition to the "Research Highlights" section of Nature Chemistry. The C&E News article titled “Tuning Up for A Breakdown” draws attention to a new class of acid-sensitive polymers. A collaborative effort among Matthew Parrott, Chris Luft...READ MORE...
C&E News Piece
Nature Chemistry piece
JACS PAPEr online
DOWNLOAD JACS PAPER

Tuesday, 18 November 2010 12:12
History Live to feature DeSimone, Tritton
On Monday, November 22nd at 5:30 p.m., the Chemical Heritage Foundation's History Live series will feature a conversation with Professor DeSimone and Tom Tritton, President and  CEO of CHF. LEARN MORE

Tuesday, 16 November 2010 13:29
Bridging science with society
Yesterday's Local Tech Wire STEM News blog post features an interview with Professor DeSimone.
Read POST

Tuesday, 02 November 2010 13:02
PRINT featured in Science News Focus piece
In a recent issue of Science, Robert Service highlights current efforts to use nanoparticles for the targeted delivery of therapeutics. learn more

Tuesday, 05 October 2010 15:11
jin_wang_sept2010
Jin Wang
JACS paper receives widespread attention
shaomin-tian
Shaomin Tian
UNC’s press release on a recent DeSimone group JACS paper, “The Complex Role of Multivalency in Nanoparticles Targeting the Transferrin Receptor for Cancer Therapies”, has seen wide circulation on the web. Highlighting findings by Jin Wang and Shaomin Tian (lead authors), the release, “Humble protein, nanoparticles tag-team to kill cancer cells”, now appears on over 40,000 websites!  LEARN MORE
READ UNC NEWS RELEASE
RELEASE ON NATIONAL CANCER INSTITUTE WEBSITE
DOWNLOAD JACS PAPER


Tuesday, 28 September 2010 16:39
$13.6 million grant from NCI
Professor DeSimone and Dr. Joel Tepper will co-lead the Carolina Center of Cancer Nanotechnology Excellence (CCNE) as it embarks on a five-year, $13.6 million effort funded by the National Cancer Institute to combat cancer.
Triangle Business Journal ARticle
PRESS RELEASE

Thursday, 26 August 2010 11:22

Notable achievements!
Liz Enlow janine_nunes
Enlow Nunes
Congratulations to Liz Enlow and Janine Nunes, who join Stuart Williams, Meredith Hampton, and Rameshwar Yadav as the most recent DeSimone Group students to obtain their PhDs! And congrats to Emily Anderson, former DeSimone student, on completing her PhD at Virginia Tech! Finally, congrats to former DeSimone Group undergrad, Courtney Fox, who has received an NSF Graduate Research Fellowship.  Read MORE

Thursday, 12 August 2010 12:29

PRINT featured on Langmuir cover
printonlangmuircoveraug2010jpg Read “Scalable, Shape-Specific, Top-Down Fabrication Methods for the Synthesis of Engineered Colloidal Particles”, by Tim Merkel, Kevin Herlihy, Janine Nunes, Ryan Orgel, Jason Rolland, and Joseph DeSimone. The paper is the cover feature for Langmuir's August 17, 2010 issue.
Tuesday, 20 July 2010 14:47

DeSimone Lemelson talk posted online
lemelsonmittalkimage1View the talk Professor DeSimone delivered after winning the 2008 Lemelson-MIT Prize.
Watch Video


Monday, 12 July 2010 12:24

Group's research featured on UNC-TV
unctvnanotechstoryimageUNC-TV recently featured a story on the impact and promises of nanotechnology. DeSimone Lab research was highlighted in the program. Watch Video

Thursday, 17 June 2010 17:20

Interventional oncology research highlighted in MIT Tech Review
implantableelectrodeimageThe DeSimone Group's research focused on implantable electrodes to treat pancreatic cancer has been featured in an MIT Technology Review article.
Read MORE

Monday, 14 June 2010 14:21


DeSimone joins Memorial Sloan-Kettering Cancer Center
Professor DeSimone has accepted an appointment with the Memorial Sloan-Kettering Cancer Center’s Cancer Nanocenter.
Read News & Observer ARticle
Read TRIANGLE BUSINESS JOURNAl article

Wednesday, 9 June 2010 09:27


Entrepreneurship blog featured
Professor DeSimone’s blog, “Reflections on Fostering Entrepreneurship in Academia”, has been featured on Engines of Innovation, a website run by UNC undergraduates that focuses on the entrepreneurial university in the 21st century. The site also features a video interview with Professor DeSimone and Bob Langer of MIT.   Read Blog   Watch Video

Friday, 28 May 2010 10:51


Holger Mißlitz takes 3rd place in CHANL Scientific Art Competition
the_trompetenblume_smDeSimone Lab visiting scholar, Holger Mißlitz, finished 3rd in the April competition with his SEM photo, “Trompetenblume”.  Read More...

Thursday, 13 May 2010 09:12

rtiimg2apr29DeSimone delivers keynote address at RTI event
Professor DeSimone visited RTI International on April 29, 2010 to give the keynote address for RTI’s 1st Innovation and Commercialization Showcase. The event theme was “Innovation Meets Impact.” DeSimone spoke on translational research, integrating diversity with innovation, and scientific achievements made through collaborative research efforts.. Read More...

Thursday, 22 April 2010 10:16
DeSimone throws out first pitch at UNC Baseball game
desimone_first_pitch_smallOn Wednesday, Professor DeSimone threw out a ceremonial first pitch before the Carolina-Davidson match up at Boshamer Stadium. UNC went on to defeat Davidson 13-0, improving their record to 26-13.
More PICTURES...
 

Featured Publications

"Rendering Protein-based Particles Transiently Insoluble for Therapeutic Applications"; Xu, J.; Wang, J.; Luft, J. C.; Tian, S.; Owens, G.; Pandya, A.; Berglund, P.; Pohlhaus, P. D.; Maynor, B. W.; Napier, M. E.; DeSimone, J. M. J. Am. Chem. Soc. 2012, DOI: DOI: 10.1021/ja302363r
jingxupaperimg1small


"Incorporation and Controlled Release of Silyl Ether Prodrugs from PRINT Nanoparticles"; Parrott, M. C.; Finniss, M. C.; Luft, J. C.; Pandya, A.; Gullapalli, A.; Napier, M. E.; DeSimone, J. M. J. Am. Chem. Soc. 2012, 134(18), 7978–7982.
mpcontrelsmall


Reductively-responsive siRNA-conjugated Hydrogel Nanoparticles for Gene Silencing"
; Dunn, S.; Tian, S.; Blake, S.; Wang, J.; Galloway, A.; Murphy, A.; Pohlhaus, P.; Rolland, J.; Napier, M.; DeSimone, J. M. J. Am. Chem. Soc. 2012, 134(17), 7423–7430.
stu_paper_apr2012_2


"Delivery of Multiple siRNAs Using Lipid-coated PLGA Nanoparticles for treatment of Prostate Cancer”; Hasan, W.; Chu, K.; Gullapalli, A.; Dunn, S. S.; Enlow, E.; Luft, J. C.; Tian, S.; Napier, M.E.; Pohlhaus, P. D.; Rolland, J. P.; DeSimone, J. M. NanoLetters 2012, 12, 287-292.
whsirna


"Tuning Multiphase Amphiphilic Rods to Direct Self-Assembly"; Wang, J. Y.; Wang, Y.; Sheiko, S. S.; Betts D. E.; Desimone, J. M. J. Am. Chem. Soc., 2012, 134(13), 5801-5806.
ywtriblock2


"
Generation of a Library of Particles Having Controlled Sizes and Shapes via the Mechanical Elongation of Master Templates"; Wang, Y.; Merkel, T. J.; Chen, K.; Fromen, C. A.; Betts, D. E.; DeSimone, J. M. Langmuir, 2011, 27(2), 524-528.
ywang_generationof2011_featpubs_smjpg


"Tunable Bifunctional Silyl Ether Cross-Linkers for the Design of Acid-Sensitive Biomaterials"; Parrott, M. C.; Luft, J. C.; Byrne, J. D.; Fain, J. H.; Napier, M. E.; DeSimone, J. M. J. Am. Chem. Soc. 2010, 132(50), 17928-17932.
mparrott_tunablebifunctional_featpubs_jpg


"Using Mechano-biological Mimicry of Red Blood Cells to Extend Circulation Times of Hydrogel Microparticles"; Merkel, T. J.; Jones, S. J.; Herlihy, K. P.; Kersey, F. R.; Shields, A. R.; Napier, M. E.; Luft, J. C.; Wu, H.; Zamboni, W. C.; Wang, A. W.; Bear, J. E.; DeSimone, J. M. Proceedings of the National Academy of Sciences, 2011, 108(2), 586-591.
tmerkel_usingmechanobiological_featpubs_jpg


"Generality of Shear Thickening in Dense Suspensions"
; Brown, E.; Forman, N.A.; Orellana, C. S.; Zhang, H.; Maynor, B. W.; Betts, D. E.; DeSimone, J. M.; Jaeger, H. M. Nature Materials 2010, 9, 220-224.
gen_of_shear_thick


"Direct Patterning of CdSe Quantum Dots into Sub-100 nm Structures"; Hampton, M. J.; Templeton, J. L.; DeSimone*, J. M.; Langmuir 2010, 26 (5), 3012-3015.
dir_patt_of_cdse


"Fabrication of Multiphasic and Regio-specifically Functionalized PRINT® Particles of Controlled Size and Shape"
; Zhang, H.; Nunes, J. K.; Gratton, S. E. A.; Herlihy, K. P.; Pohlhaus, P. D.; DeSimone, J. M.; New J. of Phys. 2009, 11 (7), 075018.
fab_of_multiphasic_and_regio


"The Effect of Particle Design on Cellular Internalization Pathways"
; Gratton, S. E. A.; Ropp, P. A.; Pohlhaus, P. D.; Luft, J. C.; Madden, V. J.; Napier, M. E.; DeSimone*, J. M. Proceedings of the National Academy of Sciences 2008, 105 (33), 11613-11618.
effect_particle_design


"The Pursuit of a Scalable Nano-fabrication Platform for Use in Material and Life Science Applications"
; Gratton, S. E. A.; Williams, S. S.; Napier, M. E.; Pohlhaus, P. D.; Zhou, Z.; Wiles, K. B.;  Maynor, B. B.; Shen, C.; Olafsen, T.; Samulski, E. T.; DeSimone*, J. M. Accounts of Chemical Research 2008, 41, 1685-1695.
pursuit_of_scalable_nanofab


"Nanostructured Titania-Polymer Photovoltaic Devices Made Using PFPE-based Nano-molding Techniques"
; Williams, S.; Hampton, M.; Gowrishanker, V.; Ding, I-K.; Templeton, J.; Samulski, E.; DeSimone*, J.M.; McGehee, M.; Chemistry of Materials, 2008, 20, 5229-5234.
nanostructured_titaniapolymer


"Shape-specific, Mono-disperse Nano-molding of Protein Particles"; Kelly, J. Y.; DeSimone*, J. M. J. Am. Chem. Soc. 2008, 130, 5438-5439.
shape_specific_monodisperse

 



DeSimone Awarded Lemelson-MIT Prize
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